Apolipoproteins in predicting risk of cardiovascular events

Even though LDL cholesterol (LDL-C) is related to an increased possibility of coronary heart ailment, other lipoproteins and their components, apolipoproteins, might play an essential role in atherosclerosis. Elevated apolipoprotein B, a component of atherogenic lipoproteins, and decreased levels of apo A-I, a component of anti-atherogenic HDL, are related to increasing cardiac events. The apo B/apo A-I and Apo B, apo A-I ratio has been reported as better forecasters of cardiovascular events than LDL-C, and they also hold on to their predictive power in patients receiving lipid-modifying therapy. Amount of these apolipoproteins can better predict cardiovascular risk prediction.

Apolipoproteins – complete health check

Apolipoprotein A test measures the amount of apolipoprotein A in your blood. It assists your healthcare provider to find out your threat for cardiovascular ailment. Apolipoprotein A is a protein carried in HDL cholesterol. It helps begin the process for HDL to eliminate bad cholesterol. In this manner, apolipoprotein A can help to decrease your risk of cardiovascular disease. Even though apolipoprotein A levels can be calculated, it is more common to measure the HDL and LDL cholesterol when looking at cardiovascular risk.

Why is this test needed?

You might need this test to see if you are at risk for heart disease. You may also require this test if you have already had heart problems such as a heart attack. This test may also assist your healthcare provider to modify your risk if you have a family history of heart disease.

The accurateness of your heart disease risk is better when both apolipoprotein A and apolipoprotein B levels are calculated and looked at together.

What do the test results indicate?

Test results can differ depending on your gender, age, health history, the technique used for the test, and other things. Your test results might not indicate you have an issue. Consult with your doctor what your test results indicate for you.

Your apolipoprotein A levels can increase if you:

  • Have an inherent disorder called CETP or familial cholesteryl ester transfer protein deficiency
  • Consume medicines having extra estrogens
  • Have increased levels of apolipoprotein
  • Take niacin
  • Lose weight
  • Take statins, a kind of cholesterol-lowering medicine

Your apolipoprotein A levels can decrease if you have:

  • Tangier disease, an uncommon hereditary disorder that reduces the amount of HDL
  • Low levels of apolipoprotein
  • Smoking habit
  • Nephritic syndrome, a group of kidney problems
  • Cholestasis, which indicates issues with the flow of bile from the liver
  • Hepatocellular disorders, which are specific types of liver issues
  • Chronic kidney (renal) failure
  • Coronary artery disease
  • Certain drugs like diuretics can decrease levels

How is this health check in Gurgaon done?

The test is carried out with a blood test. Using a needle, the blood is drawn from a vein in your arm or hand.

How to get ready for this test?

Inform your doctor if you take any medicines, such as diuretics, statins, or hormone medicine or smoke. You might need to end taking a few of these medications for the test. Ensure your doctor knows about all herbs, medications, supplements, and vitamins you are taking. It includes medicines that do not require a prescription and any illegal drugs you might use.


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